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<div class="display_title"> <h1 style="">苯、甲苯、二甲苯對上班族孕婦的影響</h1> <div class="info"> <span class="font_size">文字：<a href="javascript:setFontSize(16);">[大]</a><a href="javascript:setFontSize(14);">[中]</a><a href="javascript:setFontSize(12);">[小]</a></span> <span class="mobile_qr"> 手機頁面二維碼 <span class="qrimg"><img src="http://ibwewm.z243.ibw.cc/api/QR?t=http://hfaoyin.com/3g/display/208357.html&q=2&s=3&e=3" /></span> </span> <span class="PublishedDate">2013/10/12 </span> <span class="Hits">瀏覽次數：<b class="red" id="hits"></b> </span> <div class="share_box"> <div class="share_name">一鍵分享</div> <div style="display: none;background:#E9EBEA" class="share_content">  <div class="bdsharebuttonbox"><a href="#" class="bds_more" data-cmd="more"></a><a href="#" class="bds_qzone" data-cmd="qzone" title="分享到QQ空間"></a><a href="#" class="bds_tsina" data-cmd="tsina" title="分享到新浪微博"></a><a href="#" class="bds_renren" data-cmd="renren" title="分享到人人網"></a><a href="#" class="bds_weixin" data-cmd="weixin" title="分享到微信"></a></div> <script>window._bd_share_config = { "common": { "bdSnsKey": {}, "bdText": "", "bdMini": "2", "bdMiniList": false, "bdPic": "", "bdStyle": "0", "bdSize": "16" }, "share": {} }; with (document) 0[(getElementsByTagName('head')[0] || body).appendChild(createElement('script')).src = 'http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion=' + ~(-new Date() / 36e5)];</script>  </div> </div> <script type="text/javascript"> $('.share_box').hover(function () { $(this).find('.share_content').show(); }) $('.share_box').mouseleave(function () { $(this).find('.share_content').hide(); }) </script> </div> <div class="others enquiry"> </div>   </div> <div id="info_content" class="display_content display_article"> <p style="text-indent:2em;"> 苯及其同系物甲苯、二甲苯主要為由煤焦油分餾及裂解石油而獲得。三者均為無色透明有芳香味的液體，揮發性強。工業上利用三者之沸點不同而將其分離。但在一般情況下很難將此三者完全分離。故一般工業用苯中都含有相當量的甲苯和二甲苯，工業用甲苯中亦含有相當量的苯。因此，在生產環境空氣中，苯、甲苯、二甲苯常同時存在。煤焦油分餾及石油裂化時可接觸苯、甲苯、二甲苯;此三者均主要用做有機溶劑及化工原料。橡膠、油漆、噴漆、制藥、合成纖維(滌綸)、染料、農藥、人造革生產以及印刷業中均可接觸苯。甲苯毒性較苯低，近年來大量被用來代替苯作為橡膠、樹脂的溶劑及油漆、噴漆、油墨等的稀釋劑，亦用于炸藥、制藥及其他化工生產。二甲苯毒性較甲苯小，用作油漆、農藥的溶劑、及苯、甲苯的代替品！ </p> <p style="text-indent:2em;"> 苯主要經呼吸道吸入和經皮膚吸收，吸入體內的苯，35%-60%未經轉化即由呼氣排出，約40%于體內轉化為酚類再與硫酸根及葡萄糖醛酸結合由尿中排出。約有15%-20%蓄積于體內含脂肪較多的組織，逐漸轉化為上述代謝產物排出。 </p> <p style="text-indent:2em;"> 苯的毒性作用急性時以麻醉作用為主，慢性時則主要為抑制造血系統。急性中毒輕度中毒時可出現眼及呼吸道鉆膜刺激癥狀，不久出現頭痛、頭暈、酒醉感、倦怠、無力及惡心、嘔吐。繼之神志恍惚，步態不穩，此時如立即脫離現場，短期內可恢復。重度中毒時要發生昏迷、驚厥，呼吸表淺，脈搏細速，最后可因呼吸麻痹而死亡。 </p> <p style="text-indent:2em;"> 苯及其同系物慢性中毒后，除出現輕重不等的神經衰弱綜合征外，主要為造血系統的變化。初期白細胞總數可增高，隨著中毒的發展，周圍血液中白細胞、紅細胞和血小板皆減少，發展為全細胞貧血?；颊咴缙诩闯霈F出血傾向，如鼻衄、齒齦出血，黏膜及皮下出血，月經過多等。晚期則發展為再生障礙性貧血。苯作業工人白血病發病率比一般人群高約20倍，故認為苯中毒時尚可出現白血病。甲苯蒸氣亦主要經呼吸道侵入人體，皮膚僅能微量吸收。 </p> <p style="text-indent:2em;"> 甲苯對皮膚黏膜有較強刺激作用。急性中毒時表現為中樞神經系統的麻醉作用，慢性中毒時亦出現神經衰弱綜合征。對血液系統的毒作用不明顯。但由于工業用甲苯中常含一定量的苯，故有時亦可呈慢性苯中毒的血象變化。 </p> <p style="text-indent:2em;"> 二甲苯的侵入途徑同甲苯，急性毒性主要亦為對中樞神經系統的麻醉作用，對皮膚黏膜具有較強刺激作用。長期慢性作用可引起神經衰弱綜合征和自主神經機能失調，但其慢性作用較苯及甲苯弱。 </p> <p style="text-indent:2em;"> 有關苯及其同系物對人的生殖毒性和發育毒性資料不多。苯及其同系物可以引起女工月經異常，尤其是月經過多及經期延長較為多見，也有人報告痛經也較多見。近年來，我國對苯、甲苯、二甲苯混合物(欲稱混苯)對妊娠結局的影響進行了較多的研究，但由于樣本較小，很難做出肯定的結論。 </p> <p style="text-indent:2em;"> 資料表明，接觸苯系混合物(混苯)似乎對人胚胎發育有一定影響。而關于苯、甲苯或二甲苯單獨作用的影響，則報道更少。苯作業工人外周血液淋巴細胞及骨髓細胞染色體畸變已屢有報道，動物實驗也證明，苯可引起大白鼠骨髓細胞染色體畸變。但其對生殖細胞有否致突變作用尚未見報道。 </p> <p style="text-indent:2em;"> 動物實驗表明，高濃度或大劑量染毒時，對生殖機能及胎仔發育有影響。有人分析了接觸甲苯工齡在5年以上的女工140人的生育情況，她們在工作中接觸的甲苯濃度，高時可達每立方米200-400毫克，低者在每立方米25-50毫克。甲苯對死胎無影響，妊娠及分娩經過與對照組比較亦無顯著差異，但新生兒體重偏低者(3000克以下者)為對照組的2倍。二甲笨的生殖毒性及發育毒性報道甚少。有報告對月經有一定影響，主要表現為經血量過多及經期延長。自然流產及妊娠高血壓綜合征的發生率高于對照組。 </p> <p style="text-indent:2em;"> 苯、甲苯、二甲苯分子量低，可透過胎盤屏障而直接作用于胚胎組織；苯能使母親貧血從而可影響胎兒的營養;甲苯、二甲苯的代謝產物與甘氨酸結合后被排出，故于其轉化解毒的過程中能大量消耗母體的蛋白質貯存；苯的代謝產物酚能抑制脫氧核糖核酸的合成，凡此等等均可對胎兒發育帶來不良影響。 </p> <p 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